Safety and Efficacy of Bromodomain and Extra-Terminal Inhibitors for the Treatment of Hematological Malignancies and Solid Tumors: A Systematic Study of Clinical Trials

Background: The upregulated expression of BET proteins is closely associated with the occurrence and development of hematological malignancies and solid tumors. Several BET inhibitors have been developed, and some have been in phase I/II of clinical trials. Here, the safety, efficacy, and pharmacody...

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Vydáno v:Front Pharmacol
Hlavní autoři: Sun, Yanli, Han, Jie, Wang, Zhanzhao, Li, Xuening, Sun, Yanhua, Hu, Zhenbo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870522/
https://ncbi.nlm.nih.gov/pubmed/33574760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.621093
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