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Safety and Efficacy of Bromodomain and Extra-Terminal Inhibitors for the Treatment of Hematological Malignancies and Solid Tumors: A Systematic Study of Clinical Trials

Background: The upregulated expression of BET proteins is closely associated with the occurrence and development of hematological malignancies and solid tumors. Several BET inhibitors have been developed, and some have been in phase I/II of clinical trials. Here, the safety, efficacy, and pharmacody...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Principais autores: Sun, Yanli, Han, Jie, Wang, Zhanzhao, Li, Xuening, Sun, Yanhua, Hu, Zhenbo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870522/
https://ncbi.nlm.nih.gov/pubmed/33574760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.621093
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