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2-NPPA Mitigates Osteoclastogenesis via Reducing TRAF6-Mediated c-fos Expression

Excessive bone resorption leads to bone destruction in pathological bone diseases. Osteoporosis, which occurs when osteoclast-mediated bone resorption exceeds osteoblast-mediated bone synthesis, is regarded a global health challenge. Therefore, it is of great importance to identify agents that can r...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Chen, Zhihao, Ding, Mina, Cho, Eunjin, Seong, Jihyoun, Lee, Sunwoo, Lee, Tae-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870508/
https://ncbi.nlm.nih.gov/pubmed/33574753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.599081
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