Propionibacterium acnes Accelerates Intervertebral Disc Degeneration by Inducing Pyroptosis of Nucleus Pulposus Cells via the ROS-NLRP3 Pathway

Our previous study verified the occurrence of Propionibacterium acnes (P. acnes), a low-virulence anaerobic bacterium, latently residing in degenerated intervertebral discs (IVDs), and the infection had a strong association with IVD degeneration. We explored whether P. acnes induces nucleus pulposus...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Tang, Guoqing, Han, Xiaoguang, Lin, Zhijie, Qian, Hongbin, Chen, Bing, Zhou, Chengliang, Chen, Yong, Jiang, Weimin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870295/
https://ncbi.nlm.nih.gov/pubmed/33603947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/4657014
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