Peripheral natural killer cells in chronic hepatitis B patients display multiple molecular features of T cell exhaustion

Antiviral effectors such as natural killer (NK) cells have impaired functions in chronic hepatitis B (CHB) patients. The molecular mechanism responsible for this dysfunction remains poorly characterised. We show that decreased cytokine production capacity of peripheral NK cells from CHB patients was...

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Bibliographic Details
Published in:eLife
Main Authors: Marotel, Marie, Villard, Marine, Drouillard, Annabelle, Tout, Issam, Besson, Laurie, Allatif, Omran, Pujol, Marine, Rocca, Yamila, Ainouze, Michelle, Roblot, Guillaume, Viel, Sébastien, Gomez, Melissa, Loustaud, Veronique, Alain, Sophie, Durantel, David, Walzer, Thierry, Hasan, Uzma, Marçais, Antoine
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2021
Subjects:
Immunology and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870135/
https://ncbi.nlm.nih.gov/pubmed/33507150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60095
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