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Genetics of aldosterone-producing adenomas with pathogenic KCNJ5 variants

Somatic variants in genes that regulate intracellular ion homeostasis have been identified in aldosterone-producing adenomas (APA). Although the mechanisms leading to increased aldosterone production in APA cells has been well studied, the molecular events that cause cell proliferation and tumor for...

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Dettagli Bibliografici
Pubblicato in:Endocr Relat Cancer
Autori principali: Lerario, Antonio M., Nanba, Kazutaka, Blinder, Amy R., Suematsu, Sachiko, Omura, Masao, Nishikawa, Tetsuo, Giordano, Thomas J., Rainey, William E., Else, Tobias
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7869655/
https://ncbi.nlm.nih.gov/pubmed/30753137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-18-0364
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