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Molecular Heterogeneity in Aldosterone-Producing Adenomas

CONTEXT: The use of next-generation sequencing has resulted in the identification of recurrent somatic mutations underlying primary aldosteronism (PA). However, significant gaps remain in our understanding of the relationship between tumor aldosterone synthase (CYP11B2) expression and somatic mutati...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Nanba, Kazutaka, Chen, Andrew X., Omata, Kei, Vinco, Michelle, Giordano, Thomas J., Else, Tobias, Hammer, Gary D., Tomlins, Scott A., Rainey, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803171/
https://ncbi.nlm.nih.gov/pubmed/26765578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-3239
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