Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks

Somatic mutations have been identified in aldosterone-producing adenomas (APAs) in genes that include KCNJ5, ATP1A1, ATP2B3, and CACNA1D. Based on independent studies, there appears to be racial differences in the prevalence of somatic KCNJ5 mutations, particularly between East Asians and Europeans....

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Nanba, Kazutaka, Omata, Kei, Gomez-Sanchez, Celso E., Stratakis, Constantine A., Demidowich, Andrew P., Suzuki, Mari, Thompson, Lester D. R., Cohen, Debbie L., Luther, James M., Gellert, Lan, Vaidya, Anand, Barletta, Justine A., Else, Tobias, Giordano, Thomas J., Tomlins, Scott A., Rainey, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416065/
https://ncbi.nlm.nih.gov/pubmed/30739536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12070
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