Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks

Somatic mutations have been identified in aldosterone-producing adenomas (APAs) in genes that include KCNJ5, ATP1A1, ATP2B3, and CACNA1D. Based on independent studies, there appears to be racial differences in the prevalence of somatic KCNJ5 mutations, particularly between East Asians and Europeans....

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Pubblicato in:Hypertension
Autori principali: Nanba, Kazutaka, Omata, Kei, Gomez-Sanchez, Celso E., Stratakis, Constantine A., Demidowich, Andrew P., Suzuki, Mari, Thompson, Lester D. R., Cohen, Debbie L., Luther, James M., Gellert, Lan, Vaidya, Anand, Barletta, Justine A., Else, Tobias, Giordano, Thomas J., Tomlins, Scott A., Rainey, William E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416065/
https://ncbi.nlm.nih.gov/pubmed/30739536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12070
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