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DRPnet: automated particle picking in cryo-electron micrographs using deep regression

BACKGROUND: Identification and selection of protein particles in cryo-electron micrographs is an important step in single particle analysis. In this study, we developed a deep learning-based particle picking network to automatically detect particle centers from cryoEM micrographs. This is a challeng...

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Publicat a:BMC Bioinformatics
Autors principals: Nguyen, Nguyen Phuoc, Ersoy, Ilker, Gotberg, Jacob, Bunyak, Filiz, White, Tommi A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7869254/
https://ncbi.nlm.nih.gov/pubmed/33557750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03948-x
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