Combining vanadyl sulfate with Newcastle disease virus potentiates rapid innate immune-mediated regression with curative potential in murine cancer models

The avian paramyxovirus, Newcastle disease virus (NDV), is a promising oncolytic agent that has been shown to be safe and effective in a variety of pre-clinical cancer models and human clinical trials. NDV preferentially replicates in tumor cells due to signaling defects in apoptotic and antiviral p...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: McAusland, Thomas M., van Vloten, Jacob P., Santry, Lisa A., Guilleman, Matthew M., Rghei, Amira D., Ferreira, Edgar M., Ingrao, Joelle C., Arulanandam, Rozanne, Major, Pierre P., Susta, Leonardo, Karimi, Khalil, Diallo, Jean-Simon, Bridle, Byram W., Wootton, Sarah K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868934/
https://ncbi.nlm.nih.gov/pubmed/33614913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2021.01.009
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