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Interference chromatography: a novel approach to optimizing chromatographic selectivity and separation performance for virus purification

BACKGROUND: Oncolytic viruses are playing an increasingly important role in cancer immunotherapy applications. Given the preclinical and clinical efficacy of these virus-based therapeutics, there is a need for fast, simple, and inexpensive downstream processing methodologies to purify biologically a...

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Bibliografiske detaljer
Udgivet i:BMC Biotechnol
Main Authors: Santry, Lisa A., Jacquemart, Renaud, Vandersluis, Melissa, Zhao, Mochao, Domm, Jake M., McAusland, Thomas M., Shang, Xiaojiao, Major, Pierre M., Stout, James G., Wootton, Sarah K.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301511/
https://ncbi.nlm.nih.gov/pubmed/32552807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-020-00627-w
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