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Tanshinone IIA regulates fibroblast proliferation and migration and post-surgery arthrofibrosis through the autophagy-mediated PI3K and AMPK-mTOR signaling pathway

Post-surgery arthrofibrosis is one of the most restrictive factors in the development of intra-articular surgery and has presented tremendous obstacles for most orthopaedic surgeons. Tanshinone IIA (Tan IIA), a key active ingredient of Den-shen, has been used to treat fibrosis-related diseases, such...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Zhang, Zhen, Zhu, Dongming, Zhang, Xiaobo, Liu, Yun, Wang, Jingcheng, Yan, Lianqi
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868849/
https://ncbi.nlm.nih.gov/pubmed/33594310
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