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Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis
Hypothesis-free Mendelian randomization studies provide a way to assess the causal relevance of a trait across the human phenome but can be limited by statistical power, sample overlap or complicated by horizontal pleiotropy. The recently described latent causal variable (LCV) approach provides an a...
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| Publicado no: | Eur J Hum Genet |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7868372/ https://ncbi.nlm.nih.gov/pubmed/33011735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-020-00734-4 |
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