Mechanisms underlying pro-arrhythmic abnormalities arising from Pitx2-induced electrical remodelling: an in silico intersubject variability study

BACKGROUND: Electrical remodelling as a result of the homeodomain transcription factor 2 (Pitx2)-dependent gene regulation induces atrial fibrillation (AF) with different mechanisms. The purpose of this study was to identify Pitx2-induced changes in ionic currents that cause action potential (AP) sh...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Ann Transl Med
Egile Nagusiak: Zhu, Yijie, Bai, Jieyun, Lo, Andy, Lu, Yaosheng, Zhao, Jichao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AME Publishing Company 2021
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867875/
https://ncbi.nlm.nih.gov/pubmed/33569408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5660
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