An enhanced level of LAMP-2A participates in CD4(+)T cell hyperactivity in patients with primary biliary cholangitis

BACKGROUND: Primary biliary cholangitis (PBC) is an immune-mediated chronic cholestasis, in which T cell homeostasis plays an important role. Lysosomal-associated membrane protein 2 isoform A (LAMP-2A) has been implicated in the regulation of CD4(+)T cell responses. METHODS: We comprehensively evalu...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Sun, Keshuai, Ma, Shuoyi, Tian, Siyuan, Zhang, Miao, Liu, Yansheng, Li, Bo, Zhou, Xia, Zheng, Xiaohong, Zhou, Xinmin, Wang, Lu, Han, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867869/
https://ncbi.nlm.nih.gov/pubmed/33569403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-2427
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