Characterisation of Lamp2-deficient rats for potential new animal model of Danon disease

Danon disease (DD) is caused by the absence or malfunction of lysosomal-associated membrane protein 2 (LAMP2). Although Lamp2-deficient mice and DD patients have similar characteristics, these mice have clear limitations and are clinically inconsistent. The aim of our paper is to outline the charact...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ma, Shuoyi, Zhang, Miao, Zhang, Shuai, Wang, Jing, Zhou, Xia, Guo, Guanya, Wang, Lu, Wang, Min, Peng, Zhengwu, Guo, Changcun, Zheng, Xiaohong, Zhou, Xinmin, Wang, Jingbo, Han, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932014/
https://ncbi.nlm.nih.gov/pubmed/29720683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24351-w
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