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Role of next generation sequencing-based liquid biopsy in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors: impact of STK11, KRAS and TP53 mutations and co-mutations on outcome

BACKGROUND: Characterization of tumor-related genetic alterations is promising for the screening of new predictive markers in non-small cell lung cancer (NSCLC). Aim of the study was to evaluate prognostic and predictive role of most frequent tumor-associated genetic alterations detected in plasma b...

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Detalhes bibliográficos
Publicado no:Transl Lung Cancer Res
Main Authors: Pavan, Alberto, Bragadin, Andrea Boscolo, Calvetti, Lorenzo, Ferro, Alessandra, Zulato, Elisabetta, Attili, Ilaria, Nardo, Giorgia, Dal Maso, Alessandro, Frega, Stefano, Menin, Andrea Giovanni, Fassan, Matteo, Calabrese, Fiorella, Pasello, Giulia, Guarneri, Valentina, Aprile, Giuseppe, Conte, PierFranco, Rosell, Rafael, Indraccolo, Stefano, Bonanno, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867770/
https://ncbi.nlm.nih.gov/pubmed/33569305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-20-674
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