LKB1 and Tumor Metabolism: The Interplay of Immune and Angiogenic Microenvironment in Lung Cancer

Liver kinase B1 (LKB1) is a tumor suppressor gene whose inactivation is frequent in different tumor types, especially in lung adenocarcinoma (about 30% of cases). LKB1 has an essential role in the control of cellular redox homeostasis by regulating ROS production and detoxification. Loss of LKB1 mak...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bonanno, Laura, Zulato, Elisabetta, Pavan, Alberto, Attili, Ilaria, Pasello, Giulia, Conte, PierFranco, Indraccolo, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514929/
https://ncbi.nlm.nih.gov/pubmed/30995715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081874
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