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Tractor uses local ancestry to enable inclusion of admixed individuals into GWAS and boost power
Admixed populations are routinely excluded from genomic studies due to concerns over population structure. Here, we present a statistical framework and software package, Tractor, to facilitate inclusion of admixed individuals in association studies by leveraging local ancestry. We test Tractor with...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Genet |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7867648/ https://ncbi.nlm.nih.gov/pubmed/33462486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-00766-y |
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