Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymphoblastoid cell lines

Lymphoblastoid cell lines (LCLs) are generated by transforming primary B cells with Epstein–Barr virus (EBV) and are used extensively as model systems in viral oncology, immunology, and human genetics research. In this study, we characterized single-cell transcriptomic profiles of five LCLs and pres...

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Опубликовано в: :eLife
Главные авторы: SoRelle, Elliott D, Dai, Joanne, Bonglack, Emmanuela N, Heckenberg, Emma M, Zhou, Jeffrey Y, Giamberardino, Stephanie N, Bailey, Jeffrey A, Gregory, Simon G, Chan, Cliburn, Luftig, Micah A
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2021
Предметы:
Immunology and Inflammation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867410/
https://ncbi.nlm.nih.gov/pubmed/33501914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62586
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