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Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines

Epstein-Barr virus (EBV), an oncogenic herpesvirus, infects and transforms primary B cells into immortal lymphoblastoid cell lines (LCLs), providing a model for EBV-mediated tumorigenesis. EBV transformation stimulates robust homotypic aggregation, indicating that EBV induces molecules that mediate...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Grossman, Lisa, Chang, Chris, Dai, Joanne, Nikitin, Pavel A., Jima, Dereje D., Dave, Sandeep S., Luftig, Micah A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705804/
https://ncbi.nlm.nih.gov/pubmed/29202043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00305-17
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