Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies with limited survival rate. Roles for peptidylarginine deiminases (PADs) have been studied in relation to a range of cancers with roles in epigenetic regulation (including histone modification and microRNA regulation)...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Uysal-Onganer, Pinar, D’Alessio, Stefania, Mortoglou, Maria, Kraev, Igor, Lange, Sigrun
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866560/
https://ncbi.nlm.nih.gov/pubmed/33573274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031396
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