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Peptidylarginine Deiminase Inhibitor Cl-amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis

Deimination, a post-translational modification catalyzed by a family of enzymes called peptidylarginine deiminases (PADs), is the conversion of arginine into citrulline residues in a protein. Deimination has been associated with numerous physiological and pathological processes. Our aim was to study...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Cau, Laura, Takahara, Hidenari, Thompson, Paul R, Serre, Guy, Méchin, Marie-Claire, Simon, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708725/
https://ncbi.nlm.nih.gov/pubmed/30878672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2019.02.026
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