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Non-cell autonomous astrocyte-mediated neuronal toxicity in prion diseases

Under normal conditions, astrocytes perform a number of important physiological functions centered around neuronal support and synapse maintenance. In neurodegenerative diseases including Alzheimer’s, Parkinson’s and prion diseases, astrocytes acquire reactive phenotypes, which are sustained through...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Kushwaha, Rajesh, Sinha, Anshuman, Makarava, Natallia, Molesworth, Kara, Baskakov, Ilia V.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866439/
https://ncbi.nlm.nih.gov/pubmed/33546775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01123-8
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