Incidence of the CHEK2 Germline Mutation and Its Impact on Clinicopathological Features, Treatment Responses, and Disease Course in Patients with Papillary Thyroid Carcinoma

SIMPLE SUMMARY: The aim of our study was to evaluate whether the CHEK2 mutation was a predictor of poorer clinical course in patients with papillary thyroid cancer. The study included 1547 patients from a single center in Poland, in whom the presence and variant of the CHEK2 mutation were determined...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Gąsior-Perczak, Danuta, Kowalik, Artur, Gruszczyński, Krzysztof, Walczyk, Agnieszka, Siołek, Monika, Pałyga, Iwona, Trepka, Sławomir, Mikina, Estera, Trybek, Tomasz, Kopczyński, Janusz, Suligowska, Agnieszka, Ślusarczyk, Rafał, Gonet, Agnieszka, Jaskulski, Jarosław, Orłowski, Paweł, Chrapek, Magdalena, Góźdź, Stanisław, Kowalska, Aldona
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865996/
https://ncbi.nlm.nih.gov/pubmed/33530461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030470
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