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Diagnosis of Lynch Syndrome and Strategies to Distinguish Lynch-Related Tumors from Sporadic MSI/dMMR Tumors

SIMPLE SUMMARY: Microsatellite instability (MSI) is a hallmark of Lynch syndrome (LS)-related tumors but is not specific, as most of MSI/mismatch repair-deficient (dMMR) tumors are sporadic. Therefore, the identification of MSI/dMMR requires additional diagnostic tools to identify LS. In this review...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancers (Basel)
मुख्य लेखकों: Leclerc, Julie, Vermaut, Catherine, Buisine, Marie-Pierre
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865821/
https://ncbi.nlm.nih.gov/pubmed/33530449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030467
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