Tryptophan Pathway Abnormalities in a Murine Model of Hereditary Glaucoma

Background: It has been shown that a possible pathogenetic mechanism of neurodegeneration in the mouse model of glaucoma (DBA/2J) may be an alteration of kynurenic acid (KYNA) in the retina. This study aimed to verify the hypothesis that alterations of tryptophan (TRP) metabolism in DBA/2J mice is n...

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Publicat a:Int J Mol Sci
Autors principals: Fiedorowicz, Michal, Choragiewicz, Tomasz, Turski, Waldemar A., Kocki, Tomasz, Nowakowska, Dominika, Wertejuk, Kamila, Kamińska, Agnieszka, Avitabile, Teresio, Wełniak-Kaminska, Marlena, Grieb, Pawel, Zweifel, Sandrine, Rejdak, Robert, Toro, Mario Damiano
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865582/
https://ncbi.nlm.nih.gov/pubmed/33494373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031039
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