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HIF2alpha-Associated Pseudohypoxia Promotes Radioresistance in Pheochromocytoma: Insights from 3D Models

SIMPLE SUMMARY: Low oxygen levels (hypoxia) as well as genetic defects activating hypoxia signaling pathways (pseudohypoxia) are known to contribute to tumorigenesis and therapy resistance in various cancers. The genetic background of pheochromocytomas and paragangliomas is well characterized and in...

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書目詳細資料
發表在:Cancers (Basel)
Main Authors: Seifert, Verena, Richter, Susan, Bechmann, Nicole, Bachmann, Michael, Ziegler, Christian G., Pietzsch, Jens, Ullrich, Martin
格式: Artigo
語言:Inglês
出版: MDPI 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865577/
https://ncbi.nlm.nih.gov/pubmed/33494435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030385
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