The Novel ALG-2 Target Protein CDIP1 Promotes Cell Death by Interacting with ESCRT-I and VAPA/B

Apoptosis-linked gene 2 (ALG-2, also known as PDCD6) is a member of the penta-EF-hand (PEF) family of Ca(2+)-binding proteins. The murine gene encoding ALG-2 was originally reported to be an essential gene for apoptosis. However, the role of ALG-2 in cell death pathways has remained elusive. In the...

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Udgivet i:Int J Mol Sci
Main Authors: Inukai, Ryuta, Mori, Kanako, Kuwata, Keiko, Suzuki, Chihiro, Maki, Masatoshi, Takahara, Terunao, Shibata, Hideki
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865452/
https://ncbi.nlm.nih.gov/pubmed/33503978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031175
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