Structural Analysis of the Complex between Penta-EF-Hand ALG-2 Protein and Sec31A Peptide Reveals a Novel Target Recognition Mechanism of ALG-2

ALG-2, a 22-kDa penta-EF-hand protein, is involved in cell death, signal transduction, membrane trafficking, etc., by interacting with various proteins in mammalian cells in a Ca(2+)-dependent manner. Most known ALG-2-interacting proteins contain proline-rich regions in which either PPYPXnYP (type 1...

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Publicado en:Int J Mol Sci
Autores principales: Takahashi, Takeshi, Kojima, Kyosuke, Zhang, Wei, Sasaki, Kanae, Ito, Masaru, Suzuki, Hironori, Kawasaki, Masato, Wakatsuki, Soichi, Takahara, Terunao, Shibata, Hideki, Maki, Masatoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346919/
https://ncbi.nlm.nih.gov/pubmed/25667979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16023677
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