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Coupling of a Novel TIMP3 Peptide to Carboxypeptidase G2 for Pro-Drug Activation at the Tumour Site

Broad-spectrum cytotoxic drugs have been used in cancer therapy for decades. However, their lack of specificity to cancer cells often results in serious side-effects, limiting efficacy. For this reason, antibodies have been used to attempt to specifically target cytotoxic drugs to tumours. One such...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Aldughaim, Mohammed S., Alsaffar, Fatimah, Barker, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865317/
https://ncbi.nlm.nih.gov/pubmed/33504102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26030625
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