No Impact of NRAS Mutation on Features of Primary and Metastatic Melanoma or on Outcomes of Checkpoint Inhibitor Immunotherapy: An Italian Melanoma Intergroup (IMI) Study

SIMPLE SUMMARY: Neuroblastoma RAS Viral Oncogen Homolog (NRAS) mutant melanoma is usually considered more aggressive and more responsive to checkpoint inhibitor immunotherapy (CII) than NRAS wildtype. We retrospectively recruited 331 metastatic melanoma patients treated with CII as first line: 162 N...

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Publicado en:Cancers (Basel)
Autores principales: Guida, Michele, Bartolomeo, Nicola, Quaglino, Pietro, Madonna, Gabriele, Pigozzo, Jacopo, Di Giacomo, Anna M., Minisini, Alessandro M., Tucci, Marco, Spagnolo, Francesco, Occelli, Marcella, Ridolfi, Laura, Queirolo, Paola, De Risi, Ivana, Quaresmini, Davide, Gambale, Elisabetta, Chiaron Sileni, Vanna, Ascierto, Paolo A., Stigliano, Lucia, Strippoli, Sabino
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865301/
https://ncbi.nlm.nih.gov/pubmed/33530579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030475
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