No Impact of NRAS Mutation on Features of Primary and Metastatic Melanoma or on Outcomes of Checkpoint Inhibitor Immunotherapy: An Italian Melanoma Intergroup (IMI) Study

SIMPLE SUMMARY: Neuroblastoma RAS Viral Oncogen Homolog (NRAS) mutant melanoma is usually considered more aggressive and more responsive to checkpoint inhibitor immunotherapy (CII) than NRAS wildtype. We retrospectively recruited 331 metastatic melanoma patients treated with CII as first line: 162 N...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Guida, Michele, Bartolomeo, Nicola, Quaglino, Pietro, Madonna, Gabriele, Pigozzo, Jacopo, Di Giacomo, Anna M., Minisini, Alessandro M., Tucci, Marco, Spagnolo, Francesco, Occelli, Marcella, Ridolfi, Laura, Queirolo, Paola, De Risi, Ivana, Quaresmini, Davide, Gambale, Elisabetta, Chiaron Sileni, Vanna, Ascierto, Paolo A., Stigliano, Lucia, Strippoli, Sabino
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865301/
https://ncbi.nlm.nih.gov/pubmed/33530579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030475
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