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Role of Aiolos and Ikaros in the Antitumor and Immunomodulatory Activity of IMiDs in Multiple Myeloma: Better to Lose Than to Find Them

The Ikaros zing-finger family transcription factors (IKZF TFs) are important regulators of lymphocyte development and differentiation and are also highly expressed in B cell malignancies, including Multiple Myeloma (MM), where they are required for cancer cell growth and survival. Moreover, IKZF TFs...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Cippitelli, Marco, Stabile, Helena, Kosta, Andrea, Petillo, Sara, Gismondi, Angela, Santoni, Angela, Fionda, Cinzia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865245/
https://ncbi.nlm.nih.gov/pubmed/33499314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031103
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