Direct evidence that KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator

The gonadotropin-releasing hormone (GnRH) pulse is fundamental for mammalian reproduction: GnRH pulse regimens are needed as therapies for infertile women as continuous GnRH treatment paradoxically inhibits gonadotropin release. Circumstantial evidence suggests that the hypothalamic arcuate KNDy neu...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Nagae, Mayuko, Uenoyama, Yoshihisa, Okamoto, Saki, Tsuchida, Hitomi, Ikegami, Kana, Goto, Teppei, Majarune, Sutisa, Nakamura, Sho, Sanbo, Makoto, Hirabayashi, Masumi, Kobayashi, Kenta, Inoue, Naoko, Tsukamura, Hiroko
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2021
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865162/
https://ncbi.nlm.nih.gov/pubmed/33500349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009156118
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