Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile

Clostridioides difficile is the leading cause of nosocomial antibiotic-associated diarrhoea worldwide, yet there is little insight into intestinal tract colonisation and relapse. In many bacterial species, the secondary messenger cyclic-di-GMP mediates switching between planktonic phase, sessile gro...

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Vydáno v:Sci Rep
Hlavní autoři: Dawson, Lisa F., Peltier, Johann, Hall, Catherine L., Harrison, Mark A., Derakhshan, Maria, Shaw, Helen A., Fairweather, Neil F., Wren, Brendan W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865049/
https://ncbi.nlm.nih.gov/pubmed/33547340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78437-5
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