Clostridioides difficile para-Cresol Production Is Induced by the Precursor para-Hydroxyphenylacetate

Clostridioides difficile is an etiological agent for antibiotic-associated diarrheal disease. C. difficile produces a phenolic compound, para-cresol, which selectively targets gammaproteobacteria in the gut, facilitating dysbiosis. C. difficile decarboxylates para-hydroxyphenylacetate (p-HPA) to pro...

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Vydáno v:J Bacteriol
Hlavní autoři: Harrison, Mark A., Faulds-Pain, Alexandra, Kaur, Harparkash, Dupuy, Bruno, Henriques, Adriano O., Martin-Verstraete, Isabelle, Wren, Brendan W., Dawson, Lisa F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925072/
https://ncbi.nlm.nih.gov/pubmed/32631945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00282-20
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