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Mast cells (MCs) induce ductular reaction mimicking liver injury in mice via MC-derived TGF-β1 signaling
BACKGROUND: Following liver injury, mast cells (MCs) migrate into the liver and are activated in cholestatic patients. Inhibition of MC mediators decreases ductular reaction (DR) and liver fibrosis. TGF-β1 contributes to fibrosis and promotes liver disease. AIM: To demonstrate that reintroduction of...
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Foilsithe in: | Hepatology |
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Main Authors: | , , , , , , , , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
2021
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7864988/ https://ncbi.nlm.nih.gov/pubmed/32761972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31497 |
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