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Transcriptome comparisons of in vitro intestinal epithelia grown under static and microfluidic gut-on-chip conditions with in vivo human epithelia

Gut-on-chip devices enable exposure of cells to a continuous flow of culture medium, inducing shear stresses and could thus better recapitulate the in vivo human intestinal environment in an in vitro epithelial model compared to static culture methods. We aimed to study if dynamic culture conditions...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kulthong, Kornphimol, Hooiveld, Guido J. E. J., Duivenvoorde, Loes, Miro Estruch, Ignacio, Marin, Victor, van der Zande, Meike, Bouwmeester, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864925/
https://ncbi.nlm.nih.gov/pubmed/33547413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82853-6
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