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Dietary iso-α-acids prevent acetaldehyde-induced liver injury through Nrf2-mediated gene expression
Acetaldehyde is the major toxic metabolite of alcohol (ethanol) and enhances fibrosis of the liver through hepatic stellate cells. Additionally, alcohol administration causes the accumulation of reactive oxygen species (ROS), which induce hepatocyte injury-mediated lipid peroxidation. Iso-α-acids, c...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7864453/ https://ncbi.nlm.nih.gov/pubmed/33544749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246327 |
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