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Polydisperse molecular architecture of connexin 26/30 heteromeric hemichannels revealed by atomic force microscopy imaging

Connexin (Cx) protein forms hemichannels and gap junctional channels, which play diverse and profound roles in human physiology and diseases. Gap junctions are arrays of intercellular channels formed by the docking of two hemichannels from adjacent cells. Each hexameric hemichannel contains the same...

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Foilsithe in:J Biol Chem
Main Authors: Naulin, Pamela A., Lozano, Benjamin, Fuentes, Christian, Liu, Yu, Schmidt, Carla, Contreras, Jorge E., Barrera, Nelson P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864052/
https://ncbi.nlm.nih.gov/pubmed/32887797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012128
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