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Cutting out the fat: Site-specific deacylation of an ion channel

S-Acylation, a reversible post-translational lipid modification of proteins, controls the properties and function of various proteins, including ion channels. Large conductance Ca(2+)-activated potassium (BK) channels are S-acylated at two sites that impart distinct functional effects. Whereas the e...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: del Rivero Morfin, Pedro J., Ben-Johny, Manu
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864051/
https://ncbi.nlm.nih.gov/pubmed/33277403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H120.016490
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