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To cut or not to cut: New rules for proteolytic shedding of membrane proteins

Sheddases are specialized proteases that control the abundance and function of membrane proteins by cleaving their substrate's extracellular domain (ectodomain), a process known as shedding. Hundreds of shedding substrates have been identified, but little is known about the mechanisms that gove...

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Pubblicato in:J Biol Chem
Autori principali: Lichtenthaler, Stefan F., Meinl, Edgar
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458817/
https://ncbi.nlm.nih.gov/pubmed/32859721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H120.015304
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