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To cut or not to cut: New rules for proteolytic shedding of membrane proteins

Sheddases are specialized proteases that control the abundance and function of membrane proteins by cleaving their substrate's extracellular domain (ectodomain), a process known as shedding. Hundreds of shedding substrates have been identified, but little is known about the mechanisms that gove...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Lichtenthaler, Stefan F., Meinl, Edgar
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458817/
https://ncbi.nlm.nih.gov/pubmed/32859721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H120.015304
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