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Mycobacteria excise DNA damage in 12- or 13-nucleotide-long oligomers by prokaryotic-type dual incisions and performs transcription-coupled repair

In nucleotide excision repair, bulky DNA lesions such as UV-induced cyclobutane pyrimidine dimers are removed from the genome by concerted dual incisions bracketing the lesion, followed by gap filling and ligation. So far, two dual-incision patterns have been discovered: the prokaryotic type, which...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Selby, Christopher P., Lindsey-Boltz, Laura A., Yang, Yanyan, Sancar, Aziz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863889/
https://ncbi.nlm.nih.gov/pubmed/33087442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC120.016325
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