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Identification of a domain critical for Staphylococcus aureus LukED receptor targeting and lysis of erythrocytes

Leukocidin ED (LukED) is a pore-forming toxin produced by Staphylococcus aureus, which lyses host cells and promotes virulence of the bacteria. LukED enables S. aureus to acquire iron by lysing erythrocytes, which depends on targeting the host receptor Duffy antigen receptor for chemokines (DARC). T...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Vasquez, Marilyn T., Lubkin, Ashira, Reyes-Robles, Tamara, Day, Christopher J., Lacey, Keenan A., Jennings, Michael P., Torres, Victor J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863875/
https://ncbi.nlm.nih.gov/pubmed/33051210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015757
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