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TGFβ-1 Induced Cross-Linking of the Extracellular Matrix of Primary Human Dermal Fibroblasts

Excessive cross-linking is a major factor in the resistance to the remodelling of the extracellular matrix (ECM) during fibrotic progression. The role of TGFβ signalling in impairing ECM remodelling has been demonstrated in various fibrotic models. We hypothesised that increased ECM cross-linking by...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Semkova, Mariya E., Hsuan, J. Justin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863744/
https://ncbi.nlm.nih.gov/pubmed/33498156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22030984
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