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Retroviral overexpression of CXCR4 on murine B-1a cells and adoptive transfer for targeted B-1a cell migration to the bone marrow and IgM production

As cell function is influenced by niche-specific factors in the cellular microenvironment, methods to dissect cell localization and migration can provide further insight on cell function. B-1a cells are a unique B cell subset in mice that produce protective natural IgM antibodies against oxidation-s...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Upadhye, Aditi, Marshall, Melissa, Garmey, James C., Bender, Timothy P., McNamara, Coleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863627/
https://ncbi.nlm.nih.gov/pubmed/32538902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/61003
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