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Reduced rDNA transcription diminishes skeletal muscle ribosomal capacity and protein synthesis in cancer cachexia
Muscle wasting in cancer is associated with deficits in protein synthesis, yet the mechanisms underlying this anabolic impairment remain poorly understood. The capacity for protein synthesis is mainly determined by the abundance of muscle ribosomes, which is in turn regulated by transcription of the...
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| 出版年: | FASEB J |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7863588/ https://ncbi.nlm.nih.gov/pubmed/33527503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202002257R |
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