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Explainable drug sensitivity prediction through cancer pathway enrichment

Computational approaches to predict drug sensitivity can promote precision anticancer therapeutics. Generalizable and explainable models are of critical importance for translation to guide personalized treatment and are often overlooked in favor of prediction performance. Here, we propose PathDSP: a...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Tang, Yi-Ching, Gottlieb, Assaf
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862690/
https://ncbi.nlm.nih.gov/pubmed/33542382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82612-7
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