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Predict drug sensitivity of cancer cells with pathway activity inference

BACKGROUND: Predicting cellular responses to drugs has been a major challenge for personalized drug therapy regimen. Recent pharmacogenomic studies measured the sensitivities of heterogeneous cell lines to numerous drugs, and provided valuable data resources to develop and validate computational app...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Wang, Xuewei, Sun, Zhifu, Zimmermann, Michael T., Bugrim, Andrej, Kocher, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357358/
https://ncbi.nlm.nih.gov/pubmed/30704449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0449-4
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